diff --git a/docs/profiling.rst b/docs/profiling.rst
index e913b75..18fdf7d 100644
--- a/docs/profiling.rst
+++ b/docs/profiling.rst
@@ -46,6 +46,12 @@
         -DTFM_TOOLCHAIN_FILE=build/spe/api_ns/cmake/toolchain_ns_GNUARM.cmake
   cmake --build build/nspe -- -j
 
+.. Note::
+
+    TF-M profiling implementation relies on the physical CPU cycles provided by hardware
+    timer (refer to `Implement the HAL`_). It may not be supported on virtual platforms
+    or emulators.
+
 ******************************
 Profiler Integration Reference
 ******************************