diff --git a/programs/x509/req_app.c b/programs/x509/req_app.c
index 83e2546..b866c8e 100644
--- a/programs/x509/req_app.c
+++ b/programs/x509/req_app.c
@@ -65,6 +65,15 @@
     int i;
     char *p, *q;
 
+#if defined(MBEDTLS_USE_PSA_CRYPTO)
+    psa_status_t status = psa_crypto_init();
+    if (status != PSA_SUCCESS) {
+        mbedtls_fprintf(stderr, "Failed to initialize PSA Crypto implementation: %d\n",
+                        (int) status);
+        goto exit;
+    }
+#endif /* MBEDTLS_USE_PSA_CRYPTO */
+
     /*
      * Set to sane values
      */