diff --git a/tests/scripts/components-configuration-crypto.sh b/tests/scripts/components-configuration-crypto.sh
index 2e1326c..f8a77bb 100644
--- a/tests/scripts/components-configuration-crypto.sh
+++ b/tests/scripts/components-configuration-crypto.sh
@@ -132,6 +132,41 @@
     make test
 }
 
+component_test_full_no_cipher () {
+    msg "build: full no CIPHER"
+
+    scripts/config.py full
+    scripts/config.py unset MBEDTLS_CIPHER_C
+
+    # The built-in implementation of the following algs/key-types depends
+    # on CIPHER_C so we disable them.
+    # This does not hold for KEY_TYPE_CHACHA20 and ALG_CHACHA20_POLY1305
+    # so we keep them enabled.
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CCM_STAR_NO_TAG
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CMAC
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CBC_NO_PADDING
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CBC_PKCS7
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CFB
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_CTR
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_ECB_NO_PADDING
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_OFB
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_PBKDF2_AES_CMAC_PRF_128
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_ALG_STREAM_CIPHER
+    scripts/config.py -f $CRYPTO_CONFIG_H unset PSA_WANT_KEY_TYPE_DES
+
+    # The following modules directly depends on CIPHER_C
+    scripts/config.py unset MBEDTLS_CMAC_C
+    scripts/config.py unset MBEDTLS_NIST_KW_C
+
+    make
+
+    # Ensure that CIPHER_C was not re-enabled
+    not grep mbedtls_cipher_init ${BUILTIN_SRC_PATH}/cipher.o
+
+    msg "test: full no CIPHER"
+    make test
+}
+
 component_test_full_no_ccm() {
     msg "build: full no PSA_WANT_ALG_CCM"