diff --git a/tests/scripts/components-configuration-crypto.sh b/tests/scripts/components-configuration-crypto.sh
index 834eb1f..da776e7 100644
--- a/tests/scripts/components-configuration-crypto.sh
+++ b/tests/scripts/components-configuration-crypto.sh
@@ -515,11 +515,6 @@
     tests/scripts/depends.py cipher_chaining
 }
 
-component_test_depends_py_cipher_padding () {
-    msg "test/build: depends.py cipher_padding (gcc)"
-    tests/scripts/depends.py cipher_padding
-}
-
 component_test_depends_py_curves () {
     msg "test/build: depends.py curves (gcc)"
     tests/scripts/depends.py curves
diff --git a/tests/scripts/depends.py b/tests/scripts/depends.py
index 7fccb20..265b99f 100755
--- a/tests/scripts/depends.py
+++ b/tests/scripts/depends.py
@@ -273,13 +273,6 @@
     'PSA_WANT_ALG_OFB': ['MBEDTLS_CIPHER_MODE_OFB'],
     'PSA_WANT_ALG_XTS': ['MBEDTLS_CIPHER_MODE_XTS'],
 
-    'MBEDTLS_CIPHER_PADDING_PKCS7': ['MBEDTLS_PKCS5_C',
-                                     'MBEDTLS_PKCS12_C',
-                                     'PSA_WANT_ALG_CBC_PKCS7'],
-    'MBEDTLS_CIPHER_PADDING_ONE_AND_ZEROS': ['MBEDTLS_CIPHER_MODE_CBC'],
-    'MBEDTLS_CIPHER_PADDING_ZEROS': ['MBEDTLS_CIPHER_MODE_CBC'],
-    'MBEDTLS_CIPHER_PADDING_ZEROS_AND_LEN': ['MBEDTLS_CIPHER_MODE_CBC'],
-
     'PSA_WANT_ECC_BRAINPOOL_P_R1_256': ['MBEDTLS_ECP_DP_BP256R1_ENABLED'],
     'PSA_WANT_ECC_BRAINPOOL_P_R1_384': ['MBEDTLS_ECP_DP_BP384R1_ENABLED'],
     'PSA_WANT_ECC_BRAINPOOL_P_R1_512': ['MBEDTLS_ECP_DP_BP512R1_ENABLED'],
@@ -531,9 +524,6 @@
         # Get cipher modes
         cipher_chaining_symbols = {algs[cipher_alg] for cipher_alg in cipher_algs}
 
-        # Find block padding mode enabling macros by name.
-        cipher_padding_symbols = self.config_symbols_matching(r'MBEDTLS_CIPHER_PADDING_\w+\Z')
-
         self.domains = {
             # Cipher key types
             'cipher_id': ExclusiveDomain(cipher_key_types, build_and_test),
@@ -544,9 +534,6 @@
                                                build_and_test,
                                                exclude=r'PSA_WANT_ALG_XTS'),
 
-            'cipher_padding': ExclusiveDomain(cipher_padding_symbols,
-                                              build_and_test),
-
             # Elliptic curves. Run the test suites.
             'curves': ExclusiveDomain(curve_symbols, build_and_test),