diff --git a/boot/zephyr/Kconfig.serial_recovery b/boot/zephyr/Kconfig.serial_recovery
index 4d8f92f..63306ac 100644
--- a/boot/zephyr/Kconfig.serial_recovery
+++ b/boot/zephyr/Kconfig.serial_recovery
@@ -48,6 +48,7 @@
 
 config MCUBOOT_SERIAL_DIRECT_IMAGE_UPLOAD
 	bool "Allow to select image number for DFU"
+	depends on !SINGLE_APPLICATION_SLOT
 	help
 	  With the option enabled, the mcuboot serial recovery will
 	  respect the "image" field in mcumgr image update frame