diff --git a/boot/zephyr/Kconfig b/boot/zephyr/Kconfig
index feead57..e5a388e 100644
--- a/boot/zephyr/Kconfig
+++ b/boot/zephyr/Kconfig
@@ -271,4 +271,15 @@
 
 comment "Zephyr configuration options"
 
+# Disabling MULTITHREADING provides a code size advantage, but
+# it requires peripheral drivers (particularly a flash driver)
+# that works properly with the option enabled.
+#
+# If you know for sure that your hardware will work, you can default
+# it to n here. Otherwise, having it on by default makes the most
+# hardware work.
+config MULTITHREADING
+	default n if SOC_FAMILY_NRF
+	default y
+
 source "$ZEPHYR_BASE/Kconfig.zephyr"
diff --git a/boot/zephyr/boards/intel_s1000_crb.conf b/boot/zephyr/boards/intel_s1000_crb.conf
index e3c5ee4..ab2bfd6 100644
--- a/boot/zephyr/boards/intel_s1000_crb.conf
+++ b/boot/zephyr/boards/intel_s1000_crb.conf
@@ -1,5 +1,4 @@
 CONFIG_DEBUG=n
 CONFIG_I2C=n
 CONFIG_BOOT_MAX_IMG_SECTORS=512
-CONFIG_MULTITHREADING=y
 CONFIG_BOOT_WAIT_FOR_USB_DFU=y
diff --git a/boot/zephyr/boards/nrf52_minimal_footprint.conf b/boot/zephyr/boards/nrf52_minimal_footprint.conf
index b7aba7f..8c24f54 100644
--- a/boot/zephyr/boards/nrf52_minimal_footprint.conf
+++ b/boot/zephyr/boards/nrf52_minimal_footprint.conf
@@ -22,7 +22,6 @@
 CONFIG_SOC_NRF52832_QFAA=y
 CONFIG_ARM=y
 CONFIG_ARM_MPU=n
-# CONFIG_MULTITHREADING is not set
 CONFIG_MAIN_STACK_SIZE=10240
 CONFIG_THREAD_STACK_INFO=n
 # CONFIG_TICKLESS_KERNEL is not set
diff --git a/boot/zephyr/prj.conf b/boot/zephyr/prj.conf
index dd67333..d40307a 100644
--- a/boot/zephyr/prj.conf
+++ b/boot/zephyr/prj.conf
@@ -36,8 +36,6 @@
 
 CONFIG_FLASH=y
 
-CONFIG_MULTITHREADING=n
-
 ### Various Zephyr boards enable features that we don't want.
 # CONFIG_BT is not set
 # CONFIG_BT_CTLR is not set